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Nanoparticles

Glantreo’s proprietary platform process for the synthesis of nanoparticles has been developed over the last 12 years. The process produces scalable, durable and reproducible materials. All porous particles can be functionalised upon request.

Applications that our nano silica particles have been used for include:

  • Chromatography
  • Drug Delivery
  • Encapsulation of natural oils, flavours and heat sensitive additives
  • Catalysis
Types of nano silica particles manufactured:

  • Porous particles
  • Non-porous particles
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Non-Porous Nanoparticles

Product CodeParticle Size (µm)Pack Size (g)Surface Area (m2g-1)Chemistry
PNPP0.15NAR-100.1510<20Raw Silica
PNPP0.15NAC18-100.1510<20C18
PNPP0.15NAC4-100.1510<20C4
PNPP0.3NAR-100.310<10Raw Silica
PNPP0.3NAC18-100.310<10C18
PNPP0.3NAC4-100.310<10C4
PNPP0.5NAR-100.510<5Raw Silica
PNPP0.5NAC18-100.510<5C18
PNPP0.5NAC4-100.510<5C4

Porous Nanoparticles

Product CodeParticle size (µm)Pack sizePore Size (A)Surface Area (m2g-1)Chemistry
PFPP0.1550R-100.151050<120Raw Silica
PFPP0.3050R-100.31050<200Raw Silica
PFPP0.550R-100.51050<300Raw Silica

 

Typical Physical Properties

Purity99.99%
Particle Sizes150nm - 500nm
Pore sizes50A

 

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MSDS

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Citations using Glantreo’s materials

Patel et al., 2015, Gone in Seconds: Praxis, Performance, and Peculiarities of Ultrafast Chiral Liquid Chromatography with Superficially Porous Particles
Darshan C. Patel, Zachary S. Breitbach, M. Farooq Wahab, Chandan L. Barhate, and Daniel W. Armstrong, Gone in Seconds: Praxis, Performance, and Peculiarities of Ultrafast Chiral Liquid Chromatography with Superficially Porous Particles, Analytical Chemistry, 27 May 2015, EPub ahead of print
http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b00715
Abdallah et al., 2014, Comparison of mesoporous silicate supports for the immobilisation and activity of cytochrome c and lipase
Noreldeen H. Abdallah, Miriam Schlumpberger, Darragh A. Gaffney, John P. Hanrahan, Joseph M. Tobin, Edmond Magner, Comparison of mesoporous silicate supports for the immobilisation and activity of cytochrome c and lipase, Journal of Molecular Catalysis B: Enzymatic, Volume 108, October 2014, Pages 82-88, ISSN 1381-1177
http://www.sciencedirect.com/science/article/pii/S1381117714001805
Ahern et al., 2013, Comparison of fenofibrate–mesoporous silica drug-loading processes for enhanced drug delivery
Robert J. Ahern, John P. Hanrahan, Joseph M. Tobin, Katie B. Ryan, Abina M. Crean, Comparison of fenofibrate–mesoporous silica drug-loading processes for enhanced drug delivery, European Journal of Pharmaceutical Sciences, Volume 50, Issues 3–4, 20 November 2013, Pages 400-409, ISSN 0928-0987
http://www.sciencedirect.com/science/article/pii/S0928098713003400
Waters et al., 2013, Inclusion of fenofibrate in a series of mesoporous silicas using microwave irradiation
Laura J. Waters, Talib Hussain, Gareth Parkes, John P. Hanrahan, Joseph M. Tobin, Inclusion of fenofibrate in a series of mesoporous silicas using microwave irradiation, European Journal of Pharmaceutics and Biopharmaceutics, Volume 85, Issue 3, Part B, November 2013, Pages 936-941, ISSN 0939-6411
http://www.sciencedirect.com/science/article/pii/S0939641113002816
Omamogho et al., 2011, Structural variation of solid core and thickness of porous shell of 1.7µm core–shell silica particles on chromatographic performance: Narrow bore columns
Jesse O. Omamogho, John P. Hanrahan, Joe Tobin, Jeremy D. Glennon, Structural variation of solid core and thickness of porous shell of 1.7µm core–shell silica particles on chromatographic performance: Narrow bore columns, Journal of Chromatography A, Volume 1218, Issue 15, 15 April 2011, Pages 1942-1953, ISSN 0021-9673
http://www.sciencedirect.com/science/article/pii/S0021967310016559
Mohamed et al., 2011, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity.
Bashir Mustafa Mohamed, Navin Kumar Verma, Adriele Prina-Mello, Yvonne Williams, Anthony M Davies, Gabor Bakos, Laragh Tormey, Connla Edwards, John Hanrahan, Anna Salvati, Iseult Lynch, Kenneth Dawson, Dermot Kelleher,and Yuri Volkov, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity. Journal of Nanobiotechnology. 2011;9:29. doi:10.1186/1477-3155-9-29.
http://www.jnanobiotechnology.com/content/9/1/29
Delaney et al., 2010, Development of chemically engineered porous metal oxides for phosphate removal
Paul Delaney, Colm McManamon, John P. Hanrahan, Mark P. Copley, Justin D. Holmes, Michael A. Morris, Development of chemically engineered porous metal oxides for phosphate removal, Journal of Hazardous Materials, Volume 185, Issue 1, 15 January 2011, Pages 382-391, doi:10.1016/j.molcatb.2014.06.007.
http://www.sciencedirect.com/science/article/pii/S0304389410012069
Eltmimi et al., 2010, Preparation, characterisation and modification of carbon-based monolithic rods for chromatographic applications
Ali H. Eltmimi, Leon Barron, Aran Rafferty, John P. Hanrahan,Olga Fedyanina, Ekaterina Nesterenko, Pavel N. Nesterenko, Brett Paull, Preparation, characterisation and modification of carbon-based monolithic rods for chromatographic applications, Journal of Separation Science, Volume 33, Issue 9, 10 March 2010, Pages 1231-1243, ISSN 1615-9306 http://onlinelibrary.wiley.com/doi/10.1002/jssc.200900845/abstract
Delaney et al., 2010, Porous silica spheres as indoor air pollutant scavengers
Paul Delaney, Healy RM, Hanrahan JP, Gibson LT, Wenger JC, Morris MA, Holmes JD. Porous silica spheres as indoor air pollutant scavengers. Journal of Environmental Monitoring. 2010 Dec;12(12):2244-51. doi: 10.1039/c0em00226g.
http://www.ncbi.nlm.nih.gov/pubmed/20941430
Lynch et al., 2009, NANOINTERACT: A rational approach to the interaction between nanoscale materials and living matter
Iseult Lynch, Sara Linse, C Vyvyan Howard, Maciej Stepnik, Konrad Rydzynski, John Hanrahan, Wim de Jong, Dominique Langevin, Joachim Rädler, Wolfgang Parak, Yuri Volkov, Marek Radomski, Robert Thomas, Jacob Klein, Andrew A Barron, Colin Janssen, Fiona M Lyons, Francis Quinn, Bert Swennen, Peter Cuypers, Angela Duffy and Kenneth A Dawson, NANOINTERACT: A rational approach to the interaction between nanoscale materials and living matter, Journal of Physics: Conference Series Volume 170 Number 1.doi:10.1088/1742-6596/170/1/012040
http://iopscience.iop.org/1742-6596/170/1/012040/cites
Barnes et al. 2008, Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity.
Clifford A. Barnes, Andreas Elsaesser, Joanna Arkusz, Anna Smok, Jadwiga Palus, Anna Lesniak, Anna Salvati, John P. Hanrahan, Wim H. de Jong, Elzbieta Dziubaltowska, Maciej St?pnik, Konrad Rydzynski, George McKerr, Iseult Lynch, Kenneth A. Dawson and C. Vyvyan Howard, Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity. Nano Letters, 2008, 8 (9), pp 3069–3074. doi: 10.1021/nl801661w
http://pubs.acs.org/doi/abs/10.1021/nl801661w#citing
Barreca et al., 2006, Methanolysis of styrene oxide catalysed by a highly efficient zirconium-doped mesoporous silica
Davide Barreca, Mark P. Copley, Andrew E. Graham, Justin D. Holmes, Michael A. Morris, Roberta Seraglia, Trevor R. Spalding, Eugenio Tondello, Methanolysis of styrene oxide catalysed by a highly efficient zirconium-doped mesoporous silica, Applied Catalysis A: General, Volume 304, 10 May 2006, Pages 14-20, ISSN 0926-860X http://www.sciencedirect.com/science/article/pii/S0926860X06001013

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