Nanoparticles
Glantreo’s proprietary platform process for the synthesis of nanoparticles has been developed over the last 12 years. The process produces scalable, durable and reproducible materials. All porous particles can be functionalised upon request.
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Applications that our nano silica particles have been used for include:
- Chromatography
- Drug Delivery
- Encapsulation of natural oils, flavours and heat sensitive additives
- Catalysis
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Types of nano silica particles manufactured:
- Porous particles
- Non-porous particles
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Non-Porous Nanoparticles
| Product Code | Particle Size (µm) | Pack Size (g) | Surface Area (m2g-1) | Chemistry | |
|---|---|---|---|---|---|
| PNPP0.15NAR-10 | 0.15 | 10 | <20 | Raw Silica | |
| PNPP0.15NAC18-10 | 0.15 | 10 | <20 | C18 | |
| PNPP0.15NAC4-10 | 0.15 | 10 | <20 | C4 | |
| PNPP0.3NAR-10 | 0.3 | 10 | <10 | Raw Silica | |
| PNPP0.3NAC18-10 | 0.3 | 10 | <10 | C18 | |
| PNPP0.3NAC4-10 | 0.3 | 10 | <10 | C4 | |
| PNPP0.5NAR-10 | 0.5 | 10 | <5 | Raw Silica | |
| PNPP0.5NAC18-10 | 0.5 | 10 | <5 | C18 | |
| PNPP0.5NAC4-10 | 0.5 | 10 | <5 | C4 |
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Porous Nanoparticles
| Product Code | Particle size (µm) | Pack size | Pore Size (A) | Surface Area (m2g-1) | Chemistry |
|---|---|---|---|---|---|
| PFPP0.1550R-10 | 0.15 | 10 | 50 | <120 | Raw Silica |
| PFPP0.3050R-10 | 0.3 | 10 | 50 | <200 | Raw Silica |
| PFPP0.550R-10 | 0.5 | 10 | 50 | <300 | Raw Silica |
Typical Physical Properties
| Purity | 99.99% |
| Particle Sizes | 150nm - 500nm |
| Pore sizes | 50A |
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MSDS
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Citations using Glantreo’s materials
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[su_spoiler title=”Patel et al., 2015, Gone in Seconds: Praxis, Performance, and Peculiarities of Ultrafast Chiral Liquid Chromatography with Superficially Porous Particles”] Darshan C. Patel, Zachary S. Breitbach, M. Farooq Wahab, Chandan L. Barhate, and Daniel W. Armstrong, Gone in Seconds: Praxis, Performance, and Peculiarities of Ultrafast Chiral Liquid Chromatography with Superficially Porous Particles, Analytical Chemistry, 27 May 2015, EPub ahead of print
http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b00715
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[su_spoiler title=”Abdallah et al., 2014, Comparison of mesoporous silicate supports for the immobilisation and activity of cytochrome c and lipase”] Noreldeen H. Abdallah, Miriam Schlumpberger, Darragh A. Gaffney, John P. Hanrahan, Joseph M. Tobin, Edmond Magner, Comparison of mesoporous silicate supports for the immobilisation and activity of cytochrome c and lipase, Journal of Molecular Catalysis B: Enzymatic, Volume 108, October 2014, Pages 82-88, ISSN 1381-1177
http://www.sciencedirect.com/science/article/pii/S1381117714001805
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[su_spoiler title=”Ahern et al., 2013, Comparison of fenofibrate–mesoporous silica drug-loading processes for enhanced drug delivery”] Robert J. Ahern, John P. Hanrahan, Joseph M. Tobin, Katie B. Ryan, Abina M. Crean, Comparison of fenofibrate–mesoporous silica drug-loading processes for enhanced drug delivery, European Journal of Pharmaceutical Sciences, Volume 50, Issues 3–4, 20 November 2013, Pages 400-409, ISSN 0928-0987
http://www.sciencedirect.com/science/article/pii/S0928098713003400 [/su_spoiler]
[su_spoiler title=”Waters et al., 2013, Inclusion of fenofibrate in a series of mesoporous silicas using microwave irradiation”] Laura J. Waters, Talib Hussain, Gareth Parkes, John P. Hanrahan, Joseph M. Tobin, Inclusion of fenofibrate in a series of mesoporous silicas using microwave irradiation, European Journal of Pharmaceutics and Biopharmaceutics, Volume 85, Issue 3, Part B, November 2013, Pages 936-941, ISSN 0939-6411
http://www.sciencedirect.com/science/article/pii/S0939641113002816 [/su_spoiler]
[su_spoiler title=”Omamogho et al., 2011, Structural variation of solid core and thickness of porous shell of 1.7µm core–shell silica particles on chromatographic performance: Narrow bore columns”] Jesse O. Omamogho, John P. Hanrahan, Joe Tobin, Jeremy D. Glennon, Structural variation of solid core and thickness of porous shell of 1.7µm core–shell silica particles on chromatographic performance: Narrow bore columns, Journal of Chromatography A, Volume 1218, Issue 15, 15 April 2011, Pages 1942-1953, ISSN 0021-9673
http://www.sciencedirect.com/science/article/pii/S0021967310016559 [/su_spoiler]
[su_spoiler title=”Mohamed et al., 2011, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity.”] Bashir Mustafa Mohamed, Navin Kumar Verma, Adriele Prina-Mello, Yvonne Williams, Anthony M Davies, Gabor Bakos, Laragh Tormey, Connla Edwards, John Hanrahan, Anna Salvati, Iseult Lynch, Kenneth Dawson, Dermot Kelleher,and Yuri Volkov, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity. Journal of Nanobiotechnology. 2011;9:29. doi:10.1186/1477-3155-9-29.
http://www.jnanobiotechnology.com/content/9/1/29[/su_spoiler]
[su_spoiler title=”Delaney et al., 2010, Development of chemically engineered porous metal oxides for phosphate removal”] Paul Delaney, Colm McManamon, John P. Hanrahan, Mark P. Copley, Justin D. Holmes, Michael A. Morris, Development of chemically engineered porous metal oxides for phosphate removal, Journal of Hazardous Materials, Volume 185, Issue 1, 15 January 2011, Pages 382-391, doi:10.1016/j.molcatb.2014.06.007.
http://www.sciencedirect.com/science/article/pii/S0304389410012069
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[su_spoiler title=”Eltmimi et al., 2010, Preparation, characterisation and modification of carbon-based monolithic rods for chromatographic applications”] Ali H. Eltmimi, Leon Barron, Aran Rafferty, John P. Hanrahan,Olga Fedyanina, Ekaterina Nesterenko, Pavel N. Nesterenko, Brett Paull, Preparation, characterisation and modification of carbon-based monolithic rods for chromatographic applications, Journal of Separation Science, Volume 33, Issue 9, 10 March 2010, Pages 1231-1243, ISSN 1615-9306 http://onlinelibrary.wiley.com/doi/10.1002/jssc.200900845/abstract[/su_spoiler]
[su_spoiler title=”Delaney et al., 2010, Porous silica spheres as indoor air pollutant scavengers”] Paul Delaney, Healy RM, Hanrahan JP, Gibson LT, Wenger JC, Morris MA, Holmes JD. Porous silica spheres as indoor air pollutant scavengers. Journal of Environmental Monitoring. 2010 Dec;12(12):2244-51. doi: 10.1039/c0em00226g.
http://www.ncbi.nlm.nih.gov/pubmed/20941430
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[su_spoiler title=”Lynch et al., 2009, NANOINTERACT: A rational approach to the interaction between nanoscale materials and living matter”] Iseult Lynch, Sara Linse, C Vyvyan Howard, Maciej Stepnik, Konrad Rydzynski, John Hanrahan, Wim de Jong, Dominique Langevin, Joachim Rädler, Wolfgang Parak, Yuri Volkov, Marek Radomski, Robert Thomas, Jacob Klein, Andrew A Barron, Colin Janssen, Fiona M Lyons, Francis Quinn, Bert Swennen, Peter Cuypers, Angela Duffy and Kenneth A Dawson, NANOINTERACT: A rational approach to the interaction between nanoscale materials and living matter, Journal of Physics: Conference Series Volume 170 Number 1.doi:10.1088/1742-6596/170/1/012040
http://iopscience.iop.org/1742-6596/170/1/012040/cites[/su_spoiler]
[su_spoiler title=”Barnes et al. 2008, Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity.”] Clifford A. Barnes, Andreas Elsaesser, Joanna Arkusz, Anna Smok, Jadwiga Palus, Anna Lesniak, Anna Salvati, John P. Hanrahan, Wim H. de Jong, Elzbieta Dziubaltowska, Maciej St?pnik, Konrad Rydzynski, George McKerr, Iseult Lynch, Kenneth A. Dawson and C. Vyvyan Howard, Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity. Nano Letters, 2008, 8 (9), pp 3069–3074. doi: 10.1021/nl801661w
http://pubs.acs.org/doi/abs/10.1021/nl801661w#citing[/su_spoiler]
[su_spoiler title=”Barreca et al., 2006, Methanolysis of styrene oxide catalysed by a highly efficient zirconium-doped mesoporous silica”] Davide Barreca, Mark P. Copley, Andrew E. Graham, Justin D. Holmes, Michael A. Morris, Roberta Seraglia, Trevor R. Spalding, Eugenio Tondello, Methanolysis of styrene oxide catalysed by a highly efficient zirconium-doped mesoporous silica, Applied Catalysis A: General, Volume 304, 10 May 2006, Pages 14-20, ISSN 0926-860X http://www.sciencedirect.com/science/article/pii/S0926860X06001013[/su_spoiler]
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