Silica Gel for Liquid Chromatography SOLAS™

SOLAS™ silica gel for liquid chromatography is Glantreo’s synthesise silica. We identified a gap in the market, monodispersed silica without classification.

1. Highly monodispersed without the need to size classify leading to high chromatographic efficiency

2. Monodensity leading to higher packing stability as there are no macro pores within the particles.

3. ‘Hard Silica’ (produced with heat during manufacturing) leads to greater stability and longevity of material and columns.

The foundation of any good chromatography column is the stationary phase. We are experts in stationary phases.

SOLAS™ silica gel for liquid chromatography MonoDense™ is a proprietary process for the industries first monodense fully porous silica particle for use in HPLC and UHPLC.

Have you ever imaged fully porous silica particles using state of the art focused ion beam (FIB) milling techniques (normally utilised in microfabrication environments)? If you did you would find that the inside of traditional fully porous silica particles contains voids or holes. These voids can be up to an order of magnitude bigger than the pore size of the silica. These holes or voids cause mass transfer issues which can lead to peak broadening, peak tailing and ultimately losses in efficiency. By comparison the SOLAS™ MonoDense™ particles are monodense and contain a homogeneous pore structure which allows for the efficient transfer of analytes into and out of the silica pore structure, thereby leading to more efficient and effective chromatography. Additionally, the Glantreo particles represent a media that is easier to pack with a reduced failure rate in packing.

Product Data and References

Typical Physical Properties

Parcticle Sizes1.7um, 1.9um, 3um, 5um
Pore Size100A
Pore Volume0.65 cm3g-1
Surface Area300 m2g-1
ChemistryRaw Powder, C18, C8, C4 (others upon request)
Carbon Coverage14% (C18)
Bonding Density2.4umol/m2
Reduced Plate Height<2.5

Product Variations

Below you will find the different variations in our SOLAS™ Silica Gel For LC range. In order to make them easy to find we have added a search function. To narrow down your selection you can search within a table. If you have any questions then please do not hesitate to ‘Ask and Expert’.

Product CodeParticle SizePore SizePack sizeFunctionalisation
PFPP1.7100R-101.7um100A10gRaw silica
PFPP1.7100R-501.7um100A50gRaw silica
PFPP1.9100R-101.9um100A10gRaw silica
PFPP1.9100R-501.9um100A50gRaw silica
PFPP3.0100R-103um100A10gRaw silica
PFPP3.0100R-503um100A50gRaw silica
PFPP5.0100R-105um100A10gRaw silica
PFPP5.0100R-505um100A50gRaw silica

Citations using Glantreo’s materials

Davide Barreca, Mark P. Copley, Andrew E. Graham, Justin D. Holmes, Michael A. Morris, Roberta Seraglia, Trevor R. Spalding, Eugenio Tondello, Methanolysis of styrene oxide catalysed by a highly efficient zirconium-doped mesoporous silica, Applied Catalysis A: General, Volume 304, 10 May 2006, Pages 14-20, ISSN 0926-860X

Clifford A. Barnes, Andreas Elsaesser, Joanna Arkusz, Anna Smok, Jadwiga Palus, Anna Lesniak, Anna Salvati, John P. Hanrahan, Wim H. de Jong, Elzbieta Dziubaltowska, Maciej St?pnik, Konrad Rydzynski, George McKerr, Iseult Lynch, Kenneth A. Dawson and C. Vyvyan Howard, Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity. Nano Letters, 2008, 8 (9), pp 3069–3074. doi: 10.1021/nl801661w

Iseult Lynch, Sara Linse, C Vyvyan Howard, Maciej Stepnik, Konrad Rydzynski, John Hanrahan, Wim de Jong, Dominique Langevin, Joachim Rädler, Wolfgang Parak, Yuri Volkov, Marek Radomski, Robert Thomas, Jacob Klein, Andrew A Barron, Colin Janssen, Fiona M Lyons, Francis Quinn, Bert Swennen, Peter Cuypers, Angela Duffy and Kenneth A Dawson, NANOINTERACT: A rational approach to the interaction between nanoscale materials and living matter, Journal of Physics: Conference Series Volume 170 Number 1.doi:10.1088/1742-6596/170/1/012040

Paul Delaney, Healy RM, Hanrahan JP, Gibson LT, Wenger JC, Morris MA, Holmes JD. Porous silica spheres as indoor air pollutant scavengers. Journal of Environmental Monitoring. 2010 Dec;12(12):2244-51. doi: 10.1039/c0em00226g.

Ali H. Eltmimi, Leon Barron, Aran Rafferty, John P. Hanrahan,Olga Fedyanina, Ekaterina Nesterenko, Pavel N. Nesterenko, Brett Paull, Preparation, characterisation and modification of carbon-based monolithic rods for chromatographic applications, Journal of Separation Science, Volume 33, Issue 9, 10 March 2010, Pages 1231-1243, ISSN 1615-9306

Paul Delaney, Colm McManamon, John P. Hanrahan, Mark P. Copley, Justin D. Holmes, Michael A. Morris, Development of chemically engineered porous metal oxides for phosphate removal, Journal of Hazardous Materials, Volume 185, Issue 1, 15 January 2011, Pages 382-391, doi:10.1016/j.molcatb.2014.06.007.

Bashir Mustafa Mohamed, Navin Kumar Verma, Adriele Prina-Mello, Yvonne Williams, Anthony M Davies, Gabor Bakos, Laragh Tormey, Connla Edwards, John Hanrahan, Anna Salvati, Iseult Lynch, Kenneth Dawson, Dermot Kelleher,and Yuri Volkov, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity. Journal of Nanobiotechnology. 2011;9:29. doi:10.1186/1477-3155-9-29.

Jesse O. Omamogho, John P. Hanrahan, Joe Tobin, Jeremy D. Glennon, Structural variation of solid core and thickness of porous shell of 1.7µm core–shell silica particles on chromatographic performance: Narrow bore columns, Journal of Chromatography A, Volume 1218, Issue 15, 15 April 2011, Pages 1942-1953, ISSN 0021-9673

Laura J. Waters, Talib Hussain, Gareth Parkes, John P. Hanrahan, Joseph M. Tobin, Inclusion of fenofibrate in a series of mesoporous silicas using microwave irradiation, European Journal of Pharmaceutics and Biopharmaceutics, Volume 85, Issue 3, Part B, November 2013, Pages 936-941, ISSN 0939-6411

Robert J. Ahern, John P. Hanrahan, Joseph M. Tobin, Katie B. Ryan, Abina M. Crean, Comparison of fenofibrate–mesoporous silica drug-loading processes for enhanced drug delivery, European Journal of Pharmaceutical Sciences, Volume 50, Issues 3–4, 20 November 2013, Pages 400-409, ISSN 0928-0987

Noreldeen H. Abdallah, Miriam Schlumpberger, Darragh A. Gaffney, John P. Hanrahan, Joseph M. Tobin, Edmond Magner, Comparison of mesoporous silicate supports for the immobilisation and activity of cytochrome c and lipase, Journal of Molecular Catalysis B: Enzymatic, Volume 108, October 2014, Pages 82-88, ISSN 1381-1177

Darshan C. Patel, Zachary S. Breitbach, M. Farooq Wahab, Chandan L. Barhate, and Daniel W. Armstrong, Gone in Seconds: Praxis, Performance, and Peculiarities of Ultrafast Chiral Liquid Chromatography with Superficially Porous Particles, Analytical Chemistry, 27 May 2015, EPub ahead of print

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